2. Gene
  3. Ush1c - USH1 protein network component harmonin Gene

Ush1c - USH1 protein network component harmonin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 308596 | Gene type: protein coding

About Ush1c

Summary

Enables Myosin tail binding activity. Predicted to be involved in several processes, including brush border assembly; photoreceptor cell maintenance; and sensory organ development. Predicted to act upstream of or within neuromuscular process controlling balance and parallel actin filament bundle assembly. Located in several cellular components, including photoreceptor inner segment; photoreceptor outer segment; and stereocilium. Human ortholog(s) of this gene implicated in Usher syndrome; Usher syndrome type 1; Usher syndrome type 1C; and autosomal recessive nonsyndromic deafness 18A. Orthologous to human USH1C (USH1 protein network component harmonin). [provided by Alliance of Genome Resources, Apr 2022]

Ush1c Products(1)

mRNA Protein Name
NM_212521.2 NP_997686.2 harmonin
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in photoreceptor inner segment IDA
IDA: Inferred from direct assay
14578428 RGD
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
14578428 RGD
located in stereocilium IDA
IDA: Inferred from direct assay
16301216 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

harmonin

Usher syndrome 1C homolog

harmonin a1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15516 USH1C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21076 Ush1c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27593 Ush1c Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ush1c NCBI NCBI:10083