2. Gene
  3. Six5 - SIX homeobox 5 Gene

Six5 - SIX homeobox 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 308406 | Gene type: protein coding

About Six5

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of skeletal muscle satellite cell proliferation; negative regulation of transcription, DNA-templated; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within lens development in camera-type eye; negative regulation of cell population proliferation; and spermatid development. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in branchiootorenal syndrome 2. Orthologous to human SIX5 (SIX homeobox 5). [provided by Alliance of Genome Resources, Apr 2022]

Six5 Products(1)

mRNA Protein Name
NM_001372077.1 NP_001359006.1 homeobox protein SIX5
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
10490620 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein SIX5

sine oculis-related homeobox 5 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12962 SIX5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21435 Six5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27953 Six5 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Six5 NCBI NCBI:147912