Fndc1 - fibronectin type III domain containing 1 Gene

Rattus norvegicus

Gene ID: 308099 | Gene type: protein coding

About Fndc1

Summary

Acts upstream of or within several processes, including cellular response to hypoxia; positive regulation of cardiac muscle cell apoptotic process; and positive regulation of protein phosphorylation. Located in cell-cell junction; mitochondrial membrane; and plasma membrane. Orthologous to human FNDC1 (fibronectin type III domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Fndc1 Products(2)

mRNA	Protein	Name
NM_001038615.2	NP_001033704.2	fibronectin type III domain-containing protein 1 isoform 2 precursor
NM_001412560.1	NP_001399489.1	fibronectin type III domain-containing protein 1 isoform 1 precursor

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within cellular response to hypoxia	IMP IMP: Inferred from mutant phenotype	19723622	RGD
acts upstream of or within positive regulation of cardiac muscle cell apoptotic process	IMP IMP: Inferred from mutant phenotype	19723622	RGD
acts upstream of or within positive regulation of protein phosphorylation	IDA IDA: Inferred from direct assay	19723622	RGD
acts upstream of or within regulation of protein transport	IDA IDA: Inferred from direct assay	19723622	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in cell-cell junction	IDA IDA: Inferred from direct assay	19723622	RGD
located in cytoplasm	IDA IDA: Inferred from direct assay	19723622	RGD
located in mitochondrial membrane	IDA IDA: Inferred from direct assay	19723622	RGD
located in plasma membrane	IDA IDA: Inferred from direct assay	19723622	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

fibronectin type III domain-containing protein 1

activator of G-protein signaling 8

fibronectin type III domain containing 1 protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05018	FNDC1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS22511	Fndc1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS29032	Fndc1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Fndc1	NCBI	NCBI:84624

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