2. Gene
  3. Slc22a4 - solute carrier family 22 (organic cation transporter), member 4 Gene

Slc22a4 - solute carrier family 22 (organic cation transporter), member 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Octn1

Gene ID: 30805 | Gene type: protein coding

About Slc22a4

Summary

Enables carnitine transmembrane transporter activity. Acts upstream of or within carnitine metabolic process; carnitine transport; and triglyceride metabolic process. Located in mitochondrion. Is expressed in several structures, including integumental system; liver; musculoskeletal system; nervous system; and nose. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human SLC22A4 (solute carrier family 22 member 4). [provided by Alliance of Genome Resources, Apr 2022]

Slc22a4 Products(2)

mRNA Protein Name
NM_001330304.1 NP_001317233.1 solute carrier family 22 member 4 isoform 2
NM_019687.4 NP_062661.1 solute carrier family 22 member 4 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables carnitine transmembrane transporter activity IDA
IDA: Inferred from direct assay
11010964 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within carnitine metabolic process IGI
IGI: Inferred from genetic interaction
10655497 MGI
acts upstream of or within carnitine transport IDA
IDA: Inferred from direct assay
11010964 MGI
acts upstream of or within quaternary ammonium group transport IDA
IDA: Inferred from direct assay
11010964 MGI
acts upstream of or within triglyceride metabolic process IGI
IGI: Inferred from genetic interaction
10655497 MGI
Cellular Component GO Annotation Evidence Reference Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
15832501 MGI
located in mitochondrial membrane IDA
IDA: Inferred from direct assay
16729965 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
16729965 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

solute carrier family 22 member 4

LSTP-Like 2

organic cation/carnitine transporter 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13076 SLC22A4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19552 Slc22a4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26048 Slc22a4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc22a4 NCBI NCBI:6583