2. Gene
  3. Irx3 - iroquois homeobox 3 Gene

Irx3 - iroquois homeobox 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 307721 | Gene type: protein coding

About Irx3

Summary

Predicted to enable DNA-binding transcription activator activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including His-Purkinje system development; energy homeostasis; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within kidney development; mesoderm development; and regulation of neuron differentiation. Predicted to be located in axon; cytoplasm; and nucleus. Orthologous to human IRX3 (iroquois homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]

Irx3 Products(1)

mRNA Protein Name
NM_001395133.1 NP_001382062.1 iroquois-class homeodomain protein IRX-3
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18815185 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

iroquois-class homeodomain protein IRX-3

Iroquois related homeobox 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06922 IRX3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06925 IRX6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20756 Irx3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27269 Irx3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Irx3 NCBI NCBI:79191