2. Gene
  3. Pbrm1 - polybromo 1 Gene

Pbrm1 - polybromo 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1565549

Gene ID: 306254 | Gene type: protein coding

About Pbrm1

Summary

Predicted to enable chromatin binding activity. Involved in positive regulation of dendritic spine development. Predicted to be located in kinetochore and nucleoplasm. Predicted to be part of RSC-type complex. Human ortholog(s) of this gene implicated in extrahepatic bile duct adenocarcinoma; lung non-small cell carcinoma; lung small cell carcinoma; and renal cell carcinoma. Orthologous to human PBRM1 (polybromo 1). [provided by Alliance of Genome Resources, Apr 2022]

Pbrm1 Products(38)

mRNA Protein Name
XM_039095101.1 XP_038951029.1 protein polybromo-1 isoform X1
XM_039095118.1 XP_038951046.1 protein polybromo-1 isoform X10
XM_039095106.1 XP_038951034.1 protein polybromo-1 isoform X3
XM_039095108.1 XP_038951036.1 protein polybromo-1 isoform X4
XM_039095111.1 XP_038951039.1 protein polybromo-1 isoform X5
XM_017600287.2 XP_017455776.1 protein polybromo-1 isoform X8
XM_039095105.1 XP_038951033.1 protein polybromo-1 isoform X2
XM_039095119.1 XP_038951047.1 protein polybromo-1 isoform X11
XM_039095113.1 XP_038951041.1 protein polybromo-1 isoform X7
XM_039095123.1 XP_038951051.1 protein polybromo-1 isoform X15
XM_039095121.1 XP_038951049.1 protein polybromo-1 isoform X13
XM_039095120.1 XP_038951048.1 protein polybromo-1 isoform X12
XM_039095127.1 XP_038951055.1 protein polybromo-1 isoform X18
XM_039095112.1 XP_038951040.1 protein polybromo-1 isoform X6
XM_039095117.1 XP_038951045.1 protein polybromo-1 isoform X9
XM_017600286.2 XP_017455775.1 protein polybromo-1 isoform X8
XM_017600279.2 XP_017455768.1 protein polybromo-1 isoform X1
XM_017600281.2 XP_017455770.1 protein polybromo-1 isoform X3
XM_039095109.1 XP_038951037.1 protein polybromo-1 isoform X4
XM_017600283.2 XP_017455772.1 protein polybromo-1 isoform X5
XM_039095128.1 XP_038951056.1 protein polybromo-1 isoform X19
XM_039095124.1 XP_038951052.1 protein polybromo-1 isoform X16
XM_039095130.1 XP_038951058.1 protein polybromo-1 isoform X21
XM_039095133.1 XP_038951061.1 protein polybromo-1 isoform X24
XM_039095126.1 XP_038951054.1 protein polybromo-1 isoform X17
XM_039095122.1 XP_038951050.1 protein polybromo-1 isoform X14
XM_039095129.1 XP_038951057.1 protein polybromo-1 isoform X20
XM_039095131.1 XP_038951059.1 protein polybromo-1 isoform X22
XM_039095134.1 XP_038951062.1 protein polybromo-1 isoform X25
XM_039095132.1 XP_038951060.1 protein polybromo-1 isoform X23
XM_039095103.1 XP_038951031.1 protein polybromo-1 isoform X1
XM_039095114.1 XP_038951042.1 protein polybromo-1 isoform X8
XM_039095116.1 XP_038951044.1 protein polybromo-1 isoform X8
XM_039095104.1 XP_038951032.1 protein polybromo-1 isoform X1
XM_039095102.1 XP_038951030.1 protein polybromo-1 isoform X1
XM_006252686.3 XP_006252748.1 protein polybromo-1 isoform X1
XM_039095110.1 XP_038951038.1 protein polybromo-1 isoform X4
XM_006252696.3 XP_006252758.1 protein polybromo-1 isoform X8
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of dendritic spine development IMP
IMP: Inferred from mutant phenotype
31723243 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein polybromo-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (18)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-128359 ACBI1 99.92% Unkown
HY-163410 AU-24118 Degrader 99.10% Unkown
HY-149026 GNE-064 Inhibitor 99.65% Unkown
HY-151532 PBRM1-BD2-IN-5 Inhibitor 99.75% Unkown
HY-151538 PBRM1-BD2-IN-8 Inhibitor 99.48% Unkown
HY-150289 GNE-235 98.45% Unkown
HY-151529 PBRM1-BD2-IN-2 Inhibitor ≥99.0% Unkown
HY-151528 PBRM1-BD2-IN-1 Inhibitor / Unkown
HY-151530 PBRM1-BD2-IN-3 Inhibitor / Unkown
HY-151531 PBRM1-BD2-IN-4 Inhibitor / Unkown
HY-151533 PBRM1-BD2-IN-6 Inhibitor / Unkown
HY-151534 PBRM1-BD2-IN-7 Inhibitor / Unkown
HY-161881 SMARCA2-IN-9 Inhibitor / Unkown
HY-171774 PBRM1/SMARCA2,4-ligand-1 / Unkown
HY-174237 PBRM1/SMARCA2,4 binder-1 / Unkown
HY-RS10105 PBRM1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17918 Pbrm1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24387 Pbrm1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pbrm1 NCBI NCBI:55193