2. Gene
  3. Lats2 - large tumor suppressor kinase 2 Gene

Lats2 - large tumor suppressor kinase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 305922 | Gene type: protein coding

About Lats2

Summary

Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including G1/S transition of mitotic cell cycle; hippo signaling; and negative regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to act upstream of or within several processes, including inner cell mass cell differentiation; keratinocyte differentiation; and negative regulation of canonical Wnt signaling pathway. Predicted to be located in centriolar satellite and cytosol. Predicted to be active in nucleus and spindle pole. Orthologous to human LATS2 (large tumor suppressor kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Lats2 Products(1)

mRNA Protein Name
NM_001107267.1 NP_001100737.1 serine/threonine-protein kinase LATS2
Protein Preferred Names Protein Names

serine/threonine-protein kinase LATS2

large tumor suppressor 2

large tumor suppressor, homolog 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-138489 TRULI Modulator 99.98% Unkown
HY-147082 GA-017 Activator 98.95% Unkown
HY-W087830 L-p-Boronophenylalanine 99.84% Unkown
HY-147165 VT02956 Inhibitor 99.58% Unkown
HY-130504 Propargyl-PEG1-acid ≥97.0% Unkown
HY-RS07537 LAT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07539 LATS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-147165A VT02956 hydrochloride Inhibitor / Unkown
HY-RS18181 Lats2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21361 Lat2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24655 Lats2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27880 Lat2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lats2 NCBI NCBI:26524