2. Gene
  3. Sptbn1 - spectrin, beta, non-erythrocytic 1 Gene

Sptbn1 - spectrin, beta, non-erythrocytic 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Spnb1; Spnb2

Gene ID: 305614 | Gene type: protein coding

About Sptbn1

Summary

Predicted to enable GTPase binding activity; actin filament binding activity; and ankyrin binding activity. Predicted to be a structural constituent of Cytoskeleton. Predicted to be involved in several processes, including Golgi to plasma membrane protein transport; positive regulation of interleukin-2 production; and positive regulation of protein localization to plasma membrane. Predicted to act upstream of or within common-partner SMAD protein phosphorylation and regulation of SMAD protein signal transduction. Part of protein-containing complex. Is active in glutamatergic synapse and postsynapse. Orthologous to human SPTBN1 (spectrin beta, non-erythrocytic 1). [provided by Alliance of Genome Resources, Apr 2022]

Sptbn1 Products(1)

mRNA Protein Name
NM_001410274.1 NP_001397203.1 spectrin beta chain, non-erythrocytic 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
15331416 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
27220554 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
27220554 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
15331416 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

spectrin beta chain, non-erythrocytic 1

bSPII-

beta II spectrin-like (short form)

cytoskeleton protein

non-erythroid spectrin beta

short form of beta II spectrin

spectrin beta 2

spectrin beta chain, brain 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13732 SPTBN1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19817 Sptbn1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26313 Sptbn1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sptbn1 NCBI NCBI:6711