2. Gene
  3. Depdc5 - DEP domain containing 5, GATOR1 subcomplex subunit Gene

Depdc5 - DEP domain containing 5, GATOR1 subcomplex subunit Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 305464 | Gene type: protein coding

About Depdc5

Summary

Predicted to contribute to GTPase activator activity. Predicted to be involved in cellular response to amino acid starvation; negative regulation of TORC1 signaling; and regulation of Autophagy. Predicted to be located in cytosol; lysosome; and perinuclear region of cytoplasm. Predicted to be part of GATOR1 complex. Predicted to be active in lysosomal membrane. Human ortholog(s) of this gene implicated in focal epilepsy. Orthologous to human DEPDC5 (DEP domain containing 5, GATOR1 subcomplex subunit). [provided by Alliance of Genome Resources, Apr 2022]

Depdc5 Products(1)

mRNA Protein Name
NM_001107229.1 NP_001100699.1 GATOR complex protein DEPDC5
Protein Preferred Names Protein Names

GATOR complex protein DEPDC5

DEP domain-containing protein 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03695 DEPDC5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20545 Depdc5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27054 Depdc5 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Depdc5 NCBI NCBI:9681