2. Gene
  3. Aim2 - absent in melanoma 2 Gene

Aim2 - absent in melanoma 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 304987 | Gene type: protein coding

About Aim2

Summary

Predicted to enable double-stranded DNA binding activity and identical protein binding activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; protein-containing complex assembly; and regulation of DNA-binding transcription factor activity. Predicted to act upstream of or within cellular response to xenobiotic stimulus and positive regulation of interleukin-1 beta production. Predicted to be located in cytosol; mitochondrion; and nucleoplasm. Predicted to be part of AIM2 inflammasome complex. Orthologous to human AIM2 (absent in melanoma 2). [provided by Alliance of Genome Resources, Apr 2022]

Aim2 Products(6)

mRNA Protein Name
XM_039091426.1 XP_038947354.1 interferon-inducible protein AIM2 isoform X1
XM_222949.9 XP_222949.5 interferon-inducible protein AIM2 isoform X1
XM_008769803.2 XP_008768025.1 interferon-inducible protein AIM2 isoform X1
XM_006250336.4 XP_006250398.1 interferon-inducible protein AIM2 isoform X1
XM_008769802.3 XP_008768024.1 interferon-inducible protein AIM2 isoform X1
XM_039091427.1 XP_038947355.1 interferon-inducible protein AIM2 isoform X2
Protein Preferred Names Protein Names

interferon-inducible protein AIM2

Related Agents

Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0822 Shikonin Inhibitor 99.80% Unkown
HY-144226 NLRP3/AIM2-IN-3 Inhibitor 98.23% Unkown
HY-150751 ODN TTAGGG Antagonist 99.87% Unkown
HY-150751C ODN TTAGGG sodium Antagonist 93.80% Unkown
HY-152670 JC2-11 Inhibitor 98.03% Unkown
HY-144223 NLRP3/AIM2-IN-2 Inhibitor 99.93% Unkown
HY-138646 Poly(deoxyadenylic-thymidylic) acid sodium Activator / Unkown
HY-130480 Fructose-arginine Inhibitor 98.32% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aim2 NCBI NCBI:9447