2. Gene
  3. Abl2 - ABL proto-oncogene 2, non-receptor tyrosine kinase Gene

Abl2 - ABL proto-oncogene 2, non-receptor tyrosine kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Arg; Abll

Gene ID: 304883 | Gene type: protein coding

About Abl2

Summary

Predicted to enable metal ion binding activity; phosphotyrosine residue binding activity; and protein tyrosine kinase activity. Predicted to be involved in several processes, including cellular response to retinoic acid; peptidyl-tyrosine phosphorylation; and synapse maturation. Predicted to act upstream of or within several processes, including nervous system development; regulation of signal transduction; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in several cellular components, including dendritic spine; lamellipodium; and phagocytic cup. Predicted to be active in glutamatergic synapse. Orthologous to human ABL2 (ABL proto-oncogene 2, non-receptor tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Abl2 Products(1)

mRNA Protein Name
NM_001395130.1 NP_001382059.1 tyrosine-protein kinase ABL2
Protein Preferred Names Protein Names

tyrosine-protein kinase ABL2

Abelson murine leukemia viral (v-abl) oncogene homolog 2

Abelson tyrosine-protein kinase 2

Abl1-related gene product

arg tyrosine kinase

c-abl oncogene 2, non-receptor tyrosine kinase

v-abl Abelson murine leukemia viral oncogene 2

v-abl Abelson muri

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-148794 Risvodetinib Inhibitor 99.21% Phase 2
Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148063 DB0614 98.80% Unkown
HY-148061 DB1113 99.28% Unkown
HY-RS00105 ABL2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18744 Abl2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25231 Abl2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abl2 NCBI NCBI:27