2. Gene
  3. Tbx5 - T-box transcription factor 5 Gene

Tbx5 - T-box transcription factor 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 304514 | Gene type: protein coding

About Tbx5

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in transdifferentiation. Located in nucleus. Used to study myocardial infarction. Human ortholog(s) of this gene implicated in Holt-Oram syndrome. Orthologous to human TBX5 (T-box transcription factor 5). [provided by Alliance of Genome Resources, Apr 2022]

Tbx5 Products(1)

mRNA Protein Name
NM_001009964.1 NP_001009964.1 T-box transcription factor TBX5
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in response to aldosterone IEP
IEP: Inferred from expression pattern
29713904 RGD
involved in transdifferentiation IMP
IMP: Inferred from mutant phenotype
23948075 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

T-box transcription factor TBX5

T-box 5

T-box protein 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14281 TBX5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21440 Tbx5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27958 Tbx5 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tbx5 NCBI NCBI:6910