Abca3 - ATP binding cassette subfamily A member 3 Gene

Rattus norvegicus

Gene ID: 302973 | Gene type: protein coding

About Abca3

Summary

Predicted to enable ABC-type xenobiotic transporter activity; phosphatidylcholine flippase activity; and phosphatidylcholine transfer activity. Involved in response to glucocorticoid. Located in alveolar lamellar body membrane. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Orthologous to human ABCA3 (ATP binding cassette subfamily A member 3). [provided by Alliance of Genome Resources, Apr 2022]

Abca3 Products(1)

mRNA	Protein	Name
NM_001396034.1	NP_001382963.1	phospholipid-transporting ATPase ABCA3

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in response to glucocorticoid	IEP IEP: Inferred from expression pattern	15369786	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in alveolar lamellar body membrane	IDA IDA: Inferred from direct assay	11940594	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

phospholipid-transporting ATPase ABCA3

ATP-binding cassette sub-family A member 3

ATP-binding cassette, sub-family A (ABC1), member 3	ATP-binding cassette, subfamily A (ABC1), member 3
xenobiotic-transporting ATPase ABCA3

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00041	ABCA3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS20843	Abca3 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS27357	Abca3 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Abca3	NCBI	NCBI:21

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