2. Gene
  3. Pla2g7 - phospholipase A2 group VII Gene

Pla2g7 - phospholipase A2 group VII Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 301265 | Gene type: protein coding

About Pla2g7

Summary

Predicted to enable 1-alkyl-2-acetylglycerophosphocholine esterase activity; calcium-independent Phospholipase A2 activity; and phospholipid binding activity. Predicted to be involved in several processes, including glycerophospholipid catabolic process; plasma lipoprotein particle remodeling; and positive regulation of monocyte chemotaxis. Located in cytoplasm and extracellular space. Biomarker of nephrotic syndrome. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); glomerulonephritis (multiple); hemolytic-uremic syndrome; proteinuria (multiple); and type 2 diabetes mellitus. Orthologous to human PLA2G7 (Phospholipase A2 group VII). [provided by Alliance of Genome Resources, Apr 2022]

Pla2g7 Products(1)

mRNA Protein Name
NM_001009353.1 NP_001009353.1 platelet-activating factor acetylhydrolase precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
8692015 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

platelet-activating factor acetylhydrolase

phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-18540 KT109 Inhibitor 99.82% Unkown
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10634 PLA2G7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16659 Pla2g7 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23094 Pla2g7 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pla2g7 NCBI NCBI:7941
Mus musculus Pla2g7 NCBI NCBI:27226