2. Gene
  3. SENP1 - Senp1 SUMO specific peptidase 1 Gene

SENP1 - Senp1 SUMO specific peptidase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 300193 | Gene type: protein coding

About SENP1

Summary

Predicted to enable SUMO-specific endopeptidase activity and SUMO-specific isopeptidase activity. Predicted to be involved in activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic signaling pathway; and protein desumoylation. Predicted to act upstream of or within negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of transcription by RNA polymerase II; and regulation of definitive erythrocyte differentiation. Predicted to be located in focal adhesion; nuclear membrane; and nucleoplasm. Predicted to be active in nucleus. Orthologous to human SENP1 (SUMO specific peptidase 1). [provided by Alliance of Genome Resources, Apr 2022]

SENP1 Products(14)

mRNA Protein Name
XM_039080358.1 XP_038936286.1 sentrin-specific protease 1 isoform X6
XM_039080359.1 XP_038936287.1 sentrin-specific protease 1 isoform X6
XM_017595314.2 XP_017450803.1 sentrin-specific protease 1 isoform X2
XM_039080356.1 XP_038936284.1 sentrin-specific protease 1 isoform X1
XM_039080357.1 XP_038936285.1 sentrin-specific protease 1 isoform X6
XM_008765849.2 XP_008764071.1 sentrin-specific protease 1 isoform X8
XM_008765844.2 XP_008764066.1 sentrin-specific protease 1 isoform X4
XM_017595315.2 XP_017450804.1 sentrin-specific protease 1 isoform X3
XM_017595316.2 XP_017450805.1 sentrin-specific protease 1 isoform X5
XM_039080360.1 XP_038936288.1 sentrin-specific protease 1 isoform X10
XM_008765850.3 XP_008764072.1 sentrin-specific protease 1 isoform X9
XM_008765848.2 XP_008764070.1 sentrin-specific protease 1 isoform X7
XM_017595317.2 XP_017450806.1 sentrin-specific protease 1 isoform X6
XM_039080361.1 XP_038936289.1 sentrin-specific protease 1 isoform X11
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in regulation of postsynapse assembly IDA
IDA: Inferred from direct assay
29425794 RGD
involved in regulation of postsynapse assembly IMP
IMP: Inferred from mutant phenotype
29425794 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
29425794 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
29425794 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sentrin-specific protease 1

SUMO1/sentrin specific peptidase 1

SUMO1/sentrin specific protease 1

Sumo1/sentrin/SMT3 specific peptidase 1

sentrin-specific protease 1-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0330 Momordin Ic 99.78% Unkown
HY-N2360 Hinokiflavone 99.81% Unkown
HY-103435 Vialinin A 99.90% Unkown
HY-124586 Streptonigrin 99.20% Unkown
HY-134594 SENP1-IN-1 Inhibitor 99.55% Unkown
HY-134596 SENP1-IN-3 Inhibitor 99.92% Unkown
HY-134597 SENP1-IN-4 Inhibitor ≥98.0% Unkown
HY-151358 SENP2-IN-1 Inhibitor 98.05% Unkown
HY-134595 SENP1-IN-2 Inhibitor / Unkown
HY-RS12671 SENP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16839 Senp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23281 Senp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SENP1 NCBI NCBI:29843