2. Gene
  3. Lta4h - leukotriene A4 hydrolase Gene

Lta4h - leukotriene A4 hydrolase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 299732 | Gene type: protein coding

About Lta4h

Summary

Enables leukotriene-A4 hydrolase activity. Involved in several processes, including leukotriene metabolic process; response to zinc ion; and type I pneumocyte differentiation. Located in cytoplasm and nucleus. Biomarker of adenocarcinoma; asthma; and squamous cell carcinoma. Orthologous to human LTA4H (Leukotriene A4 hydrolase). [provided by Alliance of Genome Resources, Apr 2022]

Lta4h Products(1)

mRNA Protein Name
NM_001030031.2 NP_001025202.1 leukotriene A-4 hydrolase
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables leukotriene-A4 hydrolase activity IDA
IDA: Inferred from direct assay
3995081 RGD
Biological Process GO Annotation Evidence Reference Source
involved in leukotriene metabolic process IDA
IDA: Inferred from direct assay
3995081 RGD
involved in response to peptide hormone IEP
IEP: Inferred from expression pattern
10601658 RGD
involved in response to zinc ion IEP
IEP: Inferred from expression pattern
17985342 RGD
involved in type I pneumocyte differentiation IEP
IEP: Inferred from expression pattern
15805137 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leukotriene A-4 hydrolase

LTA-4 hydrolase

tripeptide aminopeptidase LTA4H

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0494 Bufexamac Inhibitor ≥98.0% Unkown
Pre-clinical Phase
Bioactive Molecules (18)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-137298 LYS006 Inhibitor 98.61% Unkown
HY-W004291 Methyl arachidate Inhibitor ≥98.0% Unkown
HY-W027340 ARM1 Inhibitor 99.60% Unkown
HY-W097753 4-MDM 99.64% Unkown
HY-10826 DG051 free acid Inhibitor / Unkown
HY-119023 JNJ-26993135 Inhibitor 99.30% Unkown
HY-156960 JNJ-40929837 Inhibitor / Unkown
HY-156960A JNJ-40929837 succinate Inhibitor / Unkown
HY-160646 LTA4H-IN-3 Inhibitor / Unkown
HY-161349 LTA4H-IN-4 Inhibitor / Unkown
HY-162710 LTA4H-IN-5 Inhibitor / Unkown
HY-N8760 Batatasin IV Inhibitor / Unkown
HY-RS07871 LTA4H Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W004291R Methyl arachidate (Standard) Inhibitor / Unkown
HY-137298A LYS006 hydrochloride Inhibitor / Unkown
HY-162015 LTA4H-IN-2 Inhibitor / Unkown
HY-RS17060 Lta4h Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23504 Lta4h Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lta4h NCBI NCBI:4048
Mus musculus Lta4h NCBI NCBI:16993