2. Gene
  3. Cry1 - cryptochrome circadian regulator 1 Gene

Cry1 - cryptochrome circadian regulator 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 299691 | Gene type: protein coding

About Cry1

Summary

This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by Clock/Arntl heterodimers but then represses this upregulation in a feedback loop using Per/Cry heterodimers to interact with Clock/Arntl. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across Plants and Animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Feb 2014]

Cry1 Products(1)

mRNA Protein Name
NM_198750.2 NP_942045.2 cryptochrome-1
Protein Preferred Names Protein Names

cryptochrome-1

cryptochrome 1 (photolyase-like)

cryptochrome circadian clock 1

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-108468 KL001 99.68% Phase 1
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-115672 KS15 99.46% Unkown
HY-134194 KL201 98.18% Unkown
HY-148764 M47 Inducer 99.90% Unkown
HY-RS03204 CRY1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16785 Cry1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23225 Cry1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cry1 NCBI NCBI:1407