2. Gene
  3. Mga - MAX gene associated Gene

Mga - MAX gene associated Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Mad5; C130042M01Rik; D030062C11Rik

Gene ID: 29808 | Gene type: protein coding

About Mga

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within cellular response to Leukemia Inhibitory Factor. Part of transcription regulator complex. Is expressed in several structures, including genitourinary system; gut; heart; nervous system; and sensory organ. Orthologous to human MGA (MAX dimerization protein MGA). [provided by Alliance of Genome Resources, Apr 2022]

Mga Products(2)

mRNA Protein Name
NM_001164274.1 NP_001157746.1 MAX gene-associated protein isoform 2
NM_013720.2 NP_038748.2 MAX gene-associated protein isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
10601024 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
10601024 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
10601024 MGI
Cellular Component GO Annotation Evidence Reference Source
part of transcription regulator complex IDA
IDA: Inferred from direct assay
10601024 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

MAX gene-associated protein

MAX-interacting protein

Max dimerization protein 5

Related Agents

Approval
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99222 Teplizumab ≥99.0% Unkown
Clinical Phase
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P9966 Enoblituzumab Inhibitor 99.16% Phase 3
HY-P990604 Anti-ADAM9 Antibody (MGA021) 97.17% Phase 2
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-111614 Melengestrol acetate Activator 99.76% Unkown
HY-171127 IMGC-936 / Unkown
HY-RS08395 MGA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-N13366 3-Methylcrotonyl CoA / Unkown
HY-RS18218 Mga Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24695 Mga Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mga NCBI NCBI:23269