Kcna3 - potassium voltage-gated channel subfamily A member 3 Gene

Rattus norvegicus

Gene ID: 29731 | Gene type: protein coding

About Kcna3

Summary

Enables delayed rectifier Potassium Channel activity and outward rectifier Potassium Channel activity. Involved in potassium ion transmembrane transport. Located in membrane raft and plasma membrane. Is integral component of plasma membrane. Is active in calyx of Held and glutamatergic synapse. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Orthologous to human KCNA3 (potassium voltage-gated channel subfamily A member 3). [provided by Alliance of Genome Resources, Apr 2022]

Kcna3 Products(1)

mRNA	Protein	Name
NM_019270.4	NP_062143.3	potassium voltage-gated channel subfamily A member 3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables delayed rectifier potassium channel activity	IMP IMP: Inferred from mutant phenotype	14602579	RGD
enables outward rectifier potassium channel activity	IMP IMP: Inferred from mutant phenotype	14602579	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	7477295	RGD
enables voltage-gated potassium channel activity	IDA IDA: Inferred from direct assay	2361015	RGD
enables voltage-gated potassium channel activity	IMP IMP: Inferred from mutant phenotype	2555158	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in corpus callosum development	IEP IEP: Inferred from expression pattern	22473424	RGD
involved in optic nerve development	IEP IEP: Inferred from expression pattern	22473424	RGD
involved in potassium ion transmembrane transport	IMP IMP: Inferred from mutant phenotype	2555158	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
is active in calyx of Held	IDA IDA: Inferred from direct assay	14614103	RGD
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	14614103	RGD
located in membrane raft	IDA IDA: Inferred from direct assay	18218624	RGD
located in plasma membrane	IDA IDA: Inferred from direct assay	18218624	RGD
located in plasma membrane	IMP IMP: Inferred from mutant phenotype	2555158	RGD
is active in postsynaptic membrane	IDA IDA: Inferred from direct assay	14614103	RGD
is active in presynaptic membrane	IDA IDA: Inferred from direct assay	14614103	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

potassium voltage-gated channel subfamily A member 3

KV3	RCK3
RGK5	potassium channel, voltage gated shaker related subfamily A, member 3
potassium voltage-gated channel, shaker-related subfamily, member 3	voltage-gated potassium channel subunit Kv1.3
voltage-gated potassium channel subunit Kv3

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07099	KCNA3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS22584	Kcna3 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS29101	Kcna3 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Kcna3	NCBI	NCBI:3738

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