2. Gene
  3. Mad2l1 - mitotic arrest deficient 2 like 1 Gene

Mad2l1 - mitotic arrest deficient 2 like 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 297176 | Gene type: protein coding

About Mad2l1

Summary

Predicted to enable protein C-terminus binding activity and protein homodimerization activity. Predicted to be involved in several processes, including establishment of centrosome localization; negative regulation of protein metabolic process; and regulation of mitotic metaphase/anaphase transition. Predicted to act upstream of or within mitotic sister chromatid segregation and negative regulation of mitotic cell cycle. Predicted to be located in several cellular components, including chromosome, centromeric region; perinuclear region of cytoplasm; and spindle. Predicted to be part of nuclear pore nuclear basket. Predicted to be active in cytoplasm; kinetochore; and nucleoplasm. Orthologous to human MAD2L1 (mitotic arrest deficient 2 like 1). [provided by Alliance of Genome Resources, Apr 2022]

Mad2l1 Products(1)

mRNA Protein Name
NM_001106594.1 NP_001100064.1 mitotic spindle assembly checkpoint protein MAD2A
Protein Preferred Names Protein Names

mitotic spindle assembly checkpoint protein MAD2A

MAD2 (mitotic arrest deficient, homolog)-like 1

MAD2 mitotic arrest deficient-like 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07949 MAD2L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07950 MAD2L1BP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20566 Mad2l1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27075 Mad2l1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mad2l1 NCBI NCBI:4085