2. Gene
  3. Gars1 - glycyl-tRNA synthetase 1 Gene

Gars1 - glycyl-tRNA synthetase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as GlyRS; RGD1559871

Gene ID: 297113 | Gene type: protein coding

About Gars1

Summary

Predicted to enable several functions, including bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity; glycine-tRNA Ligase activity; and identical protein binding activity. Predicted to be involved in diadenosine tetraphosphate biosynthetic process and tRNA aminoacylation for protein translation. Predicted to act upstream of or within glycyl-tRNA aminoacylation. Predicted to be located in several cellular components, including axon; extracellular exosome; and secretory granule. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2D and distal hereditary motor neuronopathy type 5A. Orthologous to human GARS1 (glycyl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]

Gars1 Products(1)

mRNA Protein Name
NM_001271139.2 NP_001258068.1 glycine--tRNA ligase
Protein Preferred Names Protein Names

glycine--tRNA ligase

AP-4-A synthetase

ap4A synthetase

diadenosine tetraphosphate synthetase

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05277 GAR1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS05279 GARS1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19198 Gars1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25686 Gars1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gars1 NCBI NCBI:2617