2. Gene
  3. Pon2 - paraoxonase 2 Gene

Pon2 - paraoxonase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 296851 | Gene type: protein coding

About Pon2

Summary

Predicted to enable arylesterase activity and identical protein binding activity. Involved in response to oxidative stress. Located in lysosome; mitochondrion; and nucleus. Biomarker of non-alcoholic fatty liver disease and obesity. Human ortholog(s) of this gene implicated in coronary artery disease; familial hypercholesterolemia; neurodegenerative disease (multiple); type 2 diabetes mellitus; and vascular dementia. Orthologous to human PON2 (paraoxonase 2). [provided by Alliance of Genome Resources, Apr 2022]

Pon2 Products(1)

mRNA Protein Name
NM_001013082.1 NP_001013100.1 serum paraoxonase/arylesterase 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in response to oxidative stress IEP
IEP: Inferred from expression pattern
17916643 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serum paraoxonase/arylesterase 2

A-esterase 2

PON 2

aromatic esterase 2

serum aryldialkylphosphatase 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10873 PON2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19633 Pon2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26128 Pon2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pon2 NCBI NCBI:5445