ATP2B4 - Atp2b4 ATPase plasma membrane Ca2+ transporting 4 Gene

Rattus norvegicus

Also known as PMCA4

Gene ID: 29600 | Gene type: protein coding

About ATP2B4

Summary

Enables P-type calcium transporter activity; PDZ domain binding activity; and protein kinase binding activity. Involved in several processes, including calcium ion transport; hippocampus development; and negative regulation of calcineurin-NFAT signaling cascade. Located in basolateral plasma membrane; neuron projection; and sperm principal piece. Is active in glutamatergic synapse. Is integral component of presynaptic active zone membrane. Biomarker of dystonia. Orthologous to human ATP2B4 (ATPase plasma membrane Ca2+ transporting 4). [provided by Alliance of Genome Resources, Apr 2022]

ATP2B4 Products(1)

mRNA	Protein	Name
NM_001005871.1	NP_001005871.1	plasma membrane calcium-transporting ATPase 4

Protein Preferred Names

Protein Names

plasma membrane calcium-transporting ATPase 4

ATPase, Ca++ transporting, plasma membrane 4	plasma membrane Ca2+-ATPases 4
plasma membrane calcium ATPase	plasma membrane calcium pump

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01197	ATP2B4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS20525	Atp2b4 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS27034	Atp2b4 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	ATP2B4	NCBI	NCBI:493

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