2. Gene
  3. Ptpn22 - protein tyrosine phosphatase, non-receptor type 22 Gene

Ptpn22 - protein tyrosine phosphatase, non-receptor type 22 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Ptpn8

Gene ID: 295338 | Gene type: protein coding

About Ptpn22

Summary

Enables protein tyrosine kinase binding activity. Involved in regulation of calcium ion transmembrane transport and regulation of peptidyl-tyrosine phosphorylation. Located in cytoplasm. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including Addison's disease; Meniere's disease; autoimmune disease (multiple); chronic lymphocytic leukemia; and pulmonary tuberculosis. Orthologous to human PTPN22 (protein tyrosine Phosphatase non-receptor type 22). [provided by Alliance of Genome Resources, Apr 2022]

Ptpn22 Products(2)

mRNA Protein Name
NM_001106460.1 NP_001099930.1 tyrosine-protein phosphatase non-receptor type 22
NM_001106460.1 NP_001099930.1 tyrosine-protein phosphatase non-receptor type 22
Protein Preferred Names Protein Names

tyrosine-protein phosphatase non-receptor type 22

protein tyrosine phosphatase, non-receptor type 22 (lymphoid)

protein tyrosine phosphatase, non-receptor type 8

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-139693 PTPN22-IN-1 Inhibitor 99.89% Unkown
HY-155847 LYP-IN-3 Inhibitor 99.80% Unkown
HY-155848 LYP-IN-4 Inhibitor 98.09% Unkown
HY-170564 PTPN22-IN-2 Inhibitor / Unkown
HY-RS11424 PTPN22 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17516 Ptpn22 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23973 Ptpn22 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptpn22 NCBI NCBI:26191