2. Gene
  3. Nfya - nuclear transcription factor Y subunit alpha Gene

Nfya - nuclear transcription factor Y subunit alpha Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as CBF-A; CBF-B

Gene ID: 29508 | Gene type: protein coding

About Nfya

Summary

Enables transcription coregulator binding activity. Predicted to be involved in positive regulation of transcription, DNA-templated and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of stem cell proliferation; positive regulation of transcription by RNA polymerase II; and regulation of stem cell population maintenance. Part of CCAAT-binding activity factor complex. Orthologous to human NFYA (nuclear transcription factor Y subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Nfya Products(3)

mRNA Protein Name
NM_001413345.1 NP_001400274.1 nuclear transcription factor Y subunit alpha isoform 1
NM_001413346.1 NP_001400275.1 nuclear transcription factor Y subunit alpha isoform 3
NM_012865.3 NP_036997.1 nuclear transcription factor Y subunit alpha isoform 2
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
10393239 RGD
enables transcription coregulator binding IPI
IPI: Inferred from physical interaction
21164521 RGD
Cellular Component GO Annotation Evidence Reference Source
part of CCAAT-binding factor complex IDA
IDA: Inferred from direct assay
7878029 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear transcription factor Y subunit alpha

CAAT box DNA-binding protein subunit A

CCAAT-binding transcription factor subunit A

CCAAT-binding transcription factor subunit B

nuclear transcription factor Y subunit A

nuclear transcription factor-Y alpha

Nfya Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Nfya P18576 Sp1 Rattus norvegicus Q01714
Anti Bait CoIP
10393239
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09271 NFYA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nfya NCBI NCBI:4800