2. Gene
  3. Hexb - hexosaminidase subunit beta Gene

Hexb - hexosaminidase subunit beta Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 294673 | Gene type: protein coding

About Hexb

Summary

Enables beta-N-acetylglucosaminidase activity; carbohydrate binding activity; and identical protein binding activity. Involved in N-acetylglucosamine metabolic process. Located in lysosome. Human ortholog(s) of this gene implicated in Sandhoff disease and spinal muscular atrophy. Orthologous to human HEXB (hexosaminidase subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Hexb Products(1)

mRNA Protein Name
NM_001011946.2 NP_001011946.1 beta-hexosaminidase subunit beta precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables beta-N-acetylglucosaminidase activity IDA
IDA: Inferred from direct assay
1397486 RGD
enables carbohydrate binding IDA
IDA: Inferred from direct assay
8702598 RGD
enables hexosaminidase activity IDA
IDA: Inferred from direct assay
8702598 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
1397486 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
1397486 RGD
Biological Process GO Annotation Evidence Reference Source
involved in N-acetylglucosamine metabolic process IDA
IDA: Inferred from direct assay
1397486 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-hexosaminidase subunit beta

N-acetyl-beta-glucosaminidase subunit beta

beta-N-acetylhexosaminidase subunit beta

hexosaminidase B

hexosaminidase subunit B

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-104050 M-31850 99.79% Unkown
HY-RS06143 HEXB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N12056 Cyclo(L-leucyl-L-valyl) / Unkown
HY-RS18135 Hexb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24610 Hexb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hexb NCBI NCBI:3074
Mus musculus Hexb NCBI NCBI:15212