1. Gene
  2. Rasgrp1 - RAS guanyl releasing protein 1 Gene

Rasgrp1 - RAS guanyl releasing protein 1 Gene

Rattus norvegicus

Also known as Rasgrp

Gene ID: 29434 | Gene type: protein coding

About Rasgrp1

Summary

Predicted to enable several functions, including cation binding activity; diacylglycerol binding activity; and guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including positive regulation of cytokine production; positive regulation of intracellular signal transduction; and positive regulation of lymphocyte differentiation. Predicted to act upstream of or within several processes, including activation of GTPase activity; mast cell degranulation; and regulation of phosphatidylinositol 3-kinase signaling. Predicted to be located in Golgi apparatus; cytosol; and plasma membrane. Human ortholog(s) of this gene implicated in immunodeficiency 64. Orthologous to human RASGRP1 (Ras guanyl releasing protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Rasgrp1 Products(1)

mRNA Protein Name
NM_019211.3 NP_062084.2 RAS guanyl-releasing protein 1
Protein Preferred Names Protein Names

RAS guanyl-releasing protein 1

CalDAG-GEF1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

calDAG-GEFII

calcium and DAG-regulated guanine nucleotide exchange factor II

Orthologs Information

Species Symbol Source ID
Homo sapiens Rasgrp1 NCBI NCBI:10125