Cln3 - CLN3 lysosomal/endosomal transmembrane protein, battenin Gene

Rattus norvegicus

Gene ID: 293485 | Gene type: protein coding

About Cln3

Summary

Predicted to enable calcium-dependent protein binding activity and sulfatide binding activity. Predicted to be involved in several processes, including modulation of chemical synaptic transmission; regulation of vesicle-mediated transport; and vacuole organization. Predicted to act upstream of or within several processes, including autophagosome maturation; regulation of cellular protein metabolic process; and regulation of filopodium assembly. Located in plasma membrane. Colocalizes with Golgi apparatus and endosome. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 3. Orthologous to human CLN3 (CLN3 lysosomal/endosomal transmembrane protein, battenin). [provided by Alliance of Genome Resources, Apr 2022]

Cln3 Products(1)

mRNA	Protein	Name
NM_001006971.1	NP_001006972.1	battenin

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Reference	Source
located in endosome	IDA IDA: Inferred from direct assay	15240864	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

battenin

CLN3, battenin	Cln3p
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)	ceroid-lipofuscinosis, neuronal 3

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02822	CLN3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS22121	Cln3 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS28643	Cln3 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cln3	NCBI	NCBI:1201

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