2. Gene
  3. Serpinh1 - serpin family H member 1 Gene

Serpinh1 - serpin family H member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Cbp2; Serpinh2

Gene ID: 29345 | Gene type: protein coding

About Serpinh1

Summary

Predicted to enable serine-type endopeptidase inhibitor activity and unfolded protein binding activity. Predicted to be involved in Collagen fibril organization and negative regulation of endopeptidase activity. Predicted to act upstream of or within chondrocyte development involved in endochondral bone morphogenesis; Collagen biosynthetic process; and protein maturation. Predicted to be located in endoplasmic reticulum-Golgi intermediate compartment and membrane raft. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 10 and preterm premature rupture of the membranes. Orthologous to human SERPINH1 (Serpin family H member 1). [provided by Alliance of Genome Resources, Apr 2022]

Serpinh1 Products(1)

mRNA Protein Name
NM_017173.2 NP_058869.2 serpin H1 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
12691502 RGD
involved in response to vitamin D IEP
IEP: Inferred from expression pattern
32585450 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serpin H1

47 kDa heat shock protein

GP46

collagen binding protein 2

collagen-binding protein

colligin

serine (or cysteine) peptidase inhibitor, clade H, member 1

serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1

serine (or

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12728 SERPINH1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20670 Serpinh1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27181 Serpinh1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Serpinh1 NCBI NCBI:871