2. Gene
  3. Uqcrc2 - ubiquinol cytochrome c reductase core protein 2 Gene

Uqcrc2 - ubiquinol cytochrome c reductase core protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 293448 | Gene type: protein coding

About Uqcrc2

Summary

Predicted to enable metal ion binding activity and metalloendopeptidase activity. Involved in response to xenobiotic stimulus. Located in mitochondrion. Part of mitochondrial respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 5. Orthologous to human UQCRC2 (ubiquinol-cytochrome c reductase core protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Uqcrc2 Products(1)

mRNA Protein Name
NM_001006970.1 NP_001006971.1 cytochrome b-c1 complex subunit 2, mitochondrial precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
19166612 RGD
Biological Process GO Annotation Evidence Reference Source
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
22960082 RGD
Cellular Component GO Annotation Evidence Reference Source
part of respiratory chain complex III IDA
IDA: Inferred from direct assay
12794875 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome b-c1 complex subunit 2, mitochondrial

complex III subunit 2

core protein II

ubiquinol-cytochrome C reductase complex core protein 2, mitochondrial precursor (Complex III subunit II)

ubiquinol-cytochrome c reductase core protein II

ubiquinol-cytochrome-c reductase complex core protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-134539 IMT1 Inhibitor 98.13% Unkown
HY-RS15500 UQCRC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18880 Uqcrc2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25371 Uqcrc2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Uqcrc2 NCBI NCBI:7385