Perp - p53 apoptosis effector related to PMP22 Gene

Rattus norvegicus

Gene ID: 292949 | Gene type: protein coding

About Perp

Summary

Predicted to be involved in activation of cysteine-type endopeptidase activity and cell-cell adhesion. Predicted to act upstream of or within several processes, including amelogenesis; desmosome organization; and intrinsic apoptotic signaling pathway by p53 class mediator. Predicted to be located in Golgi apparatus and mitochondrion. Predicted to be integral component of plasma membrane. Predicted to be active in cell-cell junction. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis and mutilating palmoplantar keratoderma with periorificial keratotic plaques. Orthologous to human PERP (p53 Apoptosis effector related to PMP22). [provided by Alliance of Genome Resources, Apr 2022]

Perp Products(1)

mRNA	Protein	Name
NM_001106265.2	NP_001099735.1	p53 apoptosis effector related to PMP-22

Protein Preferred Names

Protein Names

p53 apoptosis effector related to PMP-22

PERP, TP53 apoptosis effector

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10335	PERP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS18632	Perp Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS25118	Perp Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Perp	NCBI	NCBI:64065

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