2. Gene
  3. Tsg101 - tumor susceptibility 101 Gene

Tsg101 - tumor susceptibility 101 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Rw

Gene ID: 292925 | Gene type: protein coding

About Tsg101

Summary

Enables nuclear receptor coactivator activity. Involved in endosome to lysosome transport and protein monoubiquitination. Located in endosome membrane and nucleus. Human ortholog(s) of this gene implicated in breast cancer; breast carcinoma; cervix carcinoma; endometrial adenocarcinoma; and prostate Cancer. Orthologous to human TSG101 (tumor susceptibility 101). [provided by Alliance of Genome Resources, Apr 2022]

Tsg101 Products(1)

mRNA Protein Name
NM_181628.2 NP_853659.2 tumor susceptibility gene 101 protein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables nuclear receptor coactivator activity IDA
IDA: Inferred from direct assay
14761944 RGD
Biological Process GO Annotation Evidence Reference Source
involved in endosome to lysosome transport IMP
IMP: Inferred from mutant phenotype
19808888 RGD
involved in protein monoubiquitination IDA
IDA: Inferred from direct assay
14761944 RGD
Cellular Component GO Annotation Evidence Reference Source
located in endosome membrane IDA
IDA: Inferred from direct assay
11134028 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor susceptibility gene 101 protein

ESCRT-I complex subunit TSG101

Tumor supressor

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-17421 Tenatoprazole Inhibitor 99.75% Unkown
HY-P10845 KRL74 Inhibitor / Unkown
HY-RS15142 TSG101 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19082 Tsg101 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25573 Tsg101 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991414 FGI-1011A6 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tsg101 NCBI NCBI:7251