2. Gene
  3. Pdyn - prodynorphin Gene

Pdyn - prodynorphin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 29190 | Gene type: protein coding

About Pdyn

Summary

Predicted to enable Opioid Receptor binding activity. Predicted to be involved in chemical synaptic transmission; neuropeptide signaling pathway; and sensory perception. Located in cytoplasm and neuronal cell body. Is active in neuronal dense core vesicle lumen and synaptic vesicle. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 23 and temporal lobe epilepsy. Orthologous to human PDYN (prodynorphin). [provided by Alliance of Genome Resources, Apr 2022]

Pdyn Products(1)

mRNA Protein Name
NM_019374.3 NP_062247.2 proenkephalin-B preproprotein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
17064765 RGD
Biological Process GO Annotation Evidence Reference Source
involved in response to immobilization stress IEP
IEP: Inferred from expression pattern
15300902 RGD
involved in response to nicotine IEP
IEP: Inferred from expression pattern
28509375 RGD
Cellular Component GO Annotation Evidence Reference Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
16966485 RGD
located in axon terminus IDA
IDA: Inferred from direct assay
16966485 RGD
located in dendritic spine IDA
IDA: Inferred from direct assay
16966485 RGD
located in dense core granule IDA
IDA: Inferred from direct assay
16966485 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
2862008 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
16924480 RGD
is active in neuronal dense core vesicle lumen IDA
IDA: Inferred from direct assay
7911809 RGD
is active in synaptic vesicle IDA
IDA: Inferred from direct assay
7911809 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proenkephalin-B

beta-neoendorphin-dynorphin

preprodynorphin

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-176305S Neurofilament, U-15N / Unkown
HY-RS10299 PDYN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22274 Pdyn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28797 Pdyn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdyn NCBI NCBI:5173