2. Gene
  3. Rbbp8 - RB binding protein 8, endonuclease Gene

Rbbp8 - RB binding protein 8, endonuclease Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RIM; CtIP; SAE2; RBBP-8; RGD1308872

Gene ID: 291787 | Gene type: protein coding

About Rbbp8

Summary

Predicted to enable several functions, including DNA binding activity; identical protein binding activity; and single-stranded DNA endodeoxyribonuclease activity. Involved in response to estradiol. Predicted to be located in nucleoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in site of double-strand break. Human ortholog(s) of this gene implicated in Seckel syndrome 2. Orthologous to human RBBP8 (RB binding protein 8, Endonuclease). [provided by Alliance of Genome Resources, Apr 2022]

Rbbp8 Products(1)

mRNA Protein Name
NM_001134417.1 NP_001127889.1 DNA endonuclease RBBP8
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in response to estradiol IEP
IEP: Inferred from expression pattern
15473135 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA endonuclease RBBP8

ctBP-interacting protein

retinoblastoma binding protein 8

sporulation in the absence of SPO11 protein 2 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11720 RBBP8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20478 Rbbp8 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26986 Rbbp8 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rbbp8 NCBI NCBI:5932