2. Gene
  3. Dsg4 - desmoglein 4 Gene

Dsg4 - desmoglein 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 291754 | Gene type: protein coding

About Dsg4

Summary

Enables calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within BMP signaling pathway; hair follicle development; and keratinocyte differentiation. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in desmosome. Used to study hypotrichosis. Human ortholog(s) of this gene implicated in hypotrichosis and hypotrichosis 6. Orthologous to human DSG4 (desmoglein 4). [provided by Alliance of Genome Resources, Apr 2022]

Dsg4 Products(1)

mRNA Protein Name
NM_199490.2 NP_955784.1 desmoglein-4 precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables calcium ion binding IMP
IMP: Inferred from mutant phenotype
15081105 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

desmoglein-4

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04024 DSG4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19127 Dsg4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25617 Dsg4 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dsg4 NCBI NCBI:147409