2. Gene
  3. NEK1 - Nek1 NIMA-related kinase 1 Gene

NEK1 - Nek1 NIMA-related kinase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 290705 | Gene type: protein coding

About NEK1

Summary

Predicted to enable 14-3-3 protein binding activity and protein serine/threonine kinase activity. Predicted to be involved in cilium assembly; protein phosphorylation; and regulation of DNA damage checkpoint. Predicted to act upstream of or within several processes, including cellular response to DNA damage stimulus; response to ionizing radiation; and spermatogenesis. Predicted to be located in centrosome; cytosol; and nucleoplasm. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; asphyxiating thoracic dystrophy; and short-rib thoracic dysplasia 6 with or without polydactyly. Orthologous to human NEK1 (NIMA related kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

NEK1 Products(1)

mRNA Protein Name
NM_001106082.3 NP_001099552.2 serine/threonine-protein kinase Nek1
Protein Preferred Names Protein Names

serine/threonine-protein kinase Nek1

NIMA (never in mitosis gene a)-related expressed kinase 1

NIMA (never in mitosis gene a)-related kinase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-144425 BSc5367 98.65% Unkown
HY-103646 CK7 Inhibitor 99.72% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens NEK1 NCBI NCBI:4750