Crlf1 - cytokine receptor-like factor 1 Gene

About Crlf1

Summary

Predicted to enable cytokine binding activity and cytokine receptor activity. Predicted to contribute to ciliary neurotrophic factor receptor binding activity and cytokine activity. Predicted to be involved in several processes, including cytokine-mediated signaling pathway; negative regulation of motor neuron apoptotic process; and positive regulation of tyrosine phosphorylation of STAT protein. Predicted to act upstream of or within ureteric bud development. Predicted to be part of CRLF-CLCF1 complex and receptor complex. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in cold-induced sweating syndrome 1. Orthologous to human CRLF1 (cytokine receptor like factor 1). [provided by Alliance of Genome Resources, Apr 2022]