2. Gene
  3. Pdhb - pyruvate dehydrogenase E1 subunit beta Gene

Pdhb - pyruvate dehydrogenase E1 subunit beta Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 289950 | Gene type: protein coding

About Pdhb

Summary

Enables pyruvate dehydrogenase (acetyl-transferring) activity. Involved in acetyl-CoA biosynthetic process from pyruvate. Located in mitochondrion. Part of pyruvate dehydrogenase complex. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Orthologous to human PDHB (pyruvate dehydrogenase E1 subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Pdhb Products(1)

mRNA Protein Name
NM_001007620.1 NP_001007621.1 pyruvate dehydrogenase E1 component subunit beta, mitochondrial precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables pyruvate dehydrogenase (acetyl-transferring) activity IDA
IDA: Inferred from direct assay
7487891 RGD
Biological Process GO Annotation Evidence Reference Source
involved in acetyl-CoA biosynthetic process from pyruvate IDA
IDA: Inferred from direct assay
7487891 RGD
Cellular Component GO Annotation Evidence Reference Source
part of pyruvate dehydrogenase complex IDA
IDA: Inferred from direct assay
7487891 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pyruvate dehydrogenase E1 component subunit beta, mitochondrial

PDHE1-B

pyruvate dehydrogenase (lipoamide) beta

pyruvate dehydrogenase E1 beta subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10263 PDHB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21403 Pdhb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27922 Pdhb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdhb NCBI NCBI:5162