2. Gene
  3. Corin - corin, serine peptidase Gene

Corin - corin, serine peptidase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 289596 | Gene type: protein coding

About Corin

Summary

Predicted to enable serine-type endopeptidase activity. Involved in regulation of blood pressure and regulation of renal sodium excretion. Located in cytoplasmic vesicle. Is integral component of plasma membrane. Biomarker of congestive heart failure. Human ortholog(s) of this gene implicated in hypertension and pre-eclampsia. Orthologous to human CORIN (corin, serine peptidase). [provided by Alliance of Genome Resources, Apr 2022]

Corin Products(1)

mRNA Protein Name
NM_182473.2 NP_872279.2 atrial natriuretic peptide-converting enzyme
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in regulation of blood pressure IMP
IMP: Inferred from mutant phenotype
20613715 RGD
involved in regulation of renal sodium excretion IMP
IMP: Inferred from mutant phenotype
20613715 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
20613715 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
20613715 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

atrial natriuretic peptide-converting enzyme

pro-ANP-converting enzyme

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-111048 Corin Inhibitor 98.16% Unkown
HY-RS03047 CORIN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17975 Corin Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24446 Corin Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Corin NCBI NCBI:10699
Mus musculus Corin NCBI NCBI:53419