1. Gene
  2. Prg4 - proteoglycan 4 Gene

Prg4 - proteoglycan 4 Gene

Rattus norvegicus
Gene ID: 289104 | Gene type: protein coding

About Prg4

Summary

Predicted to enable polysaccharide binding activity and scavenger receptor activity. Predicted to be involved in endocytosis and immune response. Predicted to act upstream of or within hematopoietic stem cell proliferation; negative regulation of interleukin-6 production; and regulation of cell population proliferation. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome and pericarditis. Orthologous to human PRG4 (proteoglycan 4). [provided by Alliance of Genome Resources, Apr 2022]

Prg4 Products(1)

mRNA Protein Name
NM_001105962.4 NP_001099432.4 proteoglycan 4 precursor
Protein Preferred Names Protein Names

proteoglycan 4

lubricin

proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome)

Orthologs Information

Species Symbol Source ID
Homo sapiens Prg4 NCBI NCBI:10216