2. Gene
  3. Edem3 - ER degradation enhancing alpha-mannosidase like protein 3 Gene

Edem3 - ER degradation enhancing alpha-mannosidase like protein 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1561496

Gene ID: 289085 | Gene type: protein coding

About Edem3

Summary

Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in mannose trimming involved in glycoprotein ERAD pathway. Predicted to act upstream of or within glycoprotein catabolic process and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in endoplasmic reticulum lumen. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Orthologous to human EDEM3 (ER degradation enhancing alpha-mannosidase like protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Edem3 Products(1)

mRNA Protein Name
NM_001191671.1 NP_001178600.1 ER degradation-enhancing alpha-mannosidase-like protein 3
Protein Preferred Names Protein Names

ER degradation-enhancing alpha-mannosidase-like protein 3

ER degradation enhancer, mannosidase alpha-like 3

ER degradation-enhancing alpha-mannosidase-like 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04159 EDEM3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22479 Edem3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS29002 Edem3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Edem3 NCBI NCBI:80267