Diablo - diablo, IAP-binding mitochondrial protein Gene

Also known as Smac

About Diablo

Summary

Predicted to be involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; intrinsic apoptotic signaling pathway in response to oxidative stress; and neuron apoptotic process. Predicted to act upstream of or within activation of cysteine-type endopeptidase activity involved in apoptotic process. Located in cytosol and mitochondrion. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 64. Orthologous to human DIABLO (diablo IAP-binding mitochondrial protein). [provided by Alliance of Genome Resources, Apr 2022]