2. Gene
  3. Iscu - iron-sulfur cluster assembly enzyme Gene

Iscu - iron-sulfur cluster assembly enzyme Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1309562

Gene ID: 288740 | Gene type: protein coding

About Iscu

Summary

Predicted to enable 2 iron, 2 sulfur cluster binding activity; ferrous iron binding activity; and molecular adaptor activity. Predicted to be involved in several processes, including negative regulation of iron ion import across plasma membrane; positive regulation of aconitate hydratase activity; and positive regulation of mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in cytosol and mitochondrion. Predicted to be active in mitochondrial matrix. Orthologous to human ISCU (iron-sulfur cluster assembly enzyme). [provided by Alliance of Genome Resources, Apr 2022]

Iscu Products(1)

mRNA Protein Name
NM_001105936.1 NP_001099406.1 iron-sulfur cluster assembly enzyme ISCU, mitochondrial
Protein Preferred Names Protein Names

iron-sulfur cluster assembly enzyme ISCU, mitochondrial

IscU iron-sulfur cluster scaffold homolog

iron-sulfur cluster scaffold homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-145413 BRD2889 Inhibitor / Unkown
HY-RS06928 ISCU Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18618 Iscu Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25104 Iscu Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Iscu NCBI NCBI:23479