Mcm7 - minichromosome maintenance complex component 7 Gene

Rattus norvegicus

Gene ID: 288532 | Gene type: protein coding

About Mcm7

Summary

Predicted to enable single-stranded DNA binding activity. Predicted to contribute to single-stranded DNA helicase activity. Involved in cellular response to epidermal growth factor stimulus and response to xenobiotic stimulus. Located in cytosol and nucleus. Used to study hepatocellular carcinoma. Biomarker of hepatocellular carcinoma and hyperthyroidism. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human MCM7 (minichromosome maintenance complex component 7). [provided by Alliance of Genome Resources, Apr 2022]

Mcm7 Products(1)

mRNA	Protein	Name
NM_001004203.3	NP_001004203.3	DNA replication licensing factor MCM7

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to epidermal growth factor stimulus	IEP IEP: Inferred from expression pattern	19821535	RGD
involved in response to xenobiotic stimulus	IEP IEP: Inferred from expression pattern	12591091	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

DNA replication licensing factor MCM7

minichromosome maintenance deficient 7

minichromosome maintenance protein 7

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08240	MCM7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21373	Mcm7 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS27892	Mcm7 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mcm7	NCBI	NCBI:4176

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