Kpna1 - karyopherin subunit alpha 1 Gene

Rattus norvegicus

Gene ID: 288064 | Gene type: protein coding

About Kpna1

Summary

Enables nuclear localization sequence binding activity. Involved in NLS-bearing protein import into nucleus and postsynapse to nucleus signaling pathway. Located in dendrite and nucleus. Orthologous to human KPNA1 (karyopherin subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Kpna1 Products(1)

mRNA	Protein	Name
NM_198726.2	NP_942021.2	importin subunit alpha-5

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables nuclear localization sequence binding	IDA IDA: Inferred from direct assay	18303947	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	18303947	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in NLS-bearing protein import into nucleus	IMP IMP: Inferred from mutant phenotype	18303947	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in dendrite	IDA IDA: Inferred from direct assay	18303947	RGD
located in nucleus	IDA IDA: Inferred from direct assay	18303947	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

importin subunit alpha-5

importin alpha-5	importin subunit alpha-1
karyopherin alpha 1	karyopherin/importin alpha-1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07415	KPNA1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS22602	Kpna1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS29118	Kpna1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Kpna1	NCBI	NCBI:3836

Name
Email *

	Sorry, but the email address you supplied was invalid.