2. Gene
  3. Parl - presenilin associated, rhomboid-like Gene

Parl - presenilin associated, rhomboid-like Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Psarl

Gene ID: 287979 | Gene type: protein coding

About Parl

Summary

Predicted to enable serine-type endopeptidase activity. Involved in neuron differentiation and response to nutrient levels. Located in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; coronary artery disease; hyperinsulinism; myopia; and type 2 diabetes mellitus. Orthologous to human PARL (presenilin associated rhomboid like). [provided by Alliance of Genome Resources, Apr 2022]

Parl Products(2)

mRNA Protein Name
NM_001035249.1 NP_001030326.1 presenilins-associated rhomboid-like protein, mitochondrial precursor
NM_001035249.1 NP_001030326.1 presenilins-associated rhomboid-like protein, mitochondrial precursor
Protein Preferred Names Protein Names

presenilins-associated rhomboid-like protein, mitochondrial

mitochondrial intramembrane-cleaving protease PARL

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-152265A PARL-IN-1 TFA Activator / Phase 2
Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-152265 PARL-IN-1 Activator / Unkown
HY-169380 PARL-IN-2 / Unkown
HY-RS10044 PARL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18365 Parl Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24844 Parl Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Parl NCBI NCBI:55486