2. Gene
  3. Prpf8 - pre-mRNA processing factor 8 Gene

Prpf8 - pre-mRNA processing factor 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 287530 | Gene type: protein coding

About Prpf8

Summary

Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity; pre-mRNA intronic binding activity; and snRNA binding activity. Involved in cellular response to lipopolysaccharide and cellular response to tumor necrosis factor. Part of small nuclear ribonucleoprotein complex. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 13. Orthologous to human PRPF8 (pre-mRNA processing factor 8). [provided by Alliance of Genome Resources, Apr 2022]

Prpf8 Products(1)

mRNA Protein Name
NM_001191590.1 NP_001178519.1 pre-mRNA-processing-splicing factor 8
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
1707521 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
1345341 RGD
involved in cellular response to tumor necrosis factor IDA
IDA: Inferred from direct assay
1345341 RGD
Cellular Component GO Annotation Evidence Reference Source
part of small nuclear ribonucleoprotein complex IDA
IDA: Inferred from direct assay
1707521 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pre-mRNA-processing-splicing factor 8

PRP8 pre-mRNA processing factor 8 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11216 PRPF8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21700 Prpf8 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS28218 Prpf8 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prpf8 NCBI NCBI:10594