Taok1 - TAO kinase 1 Gene

Rattus norvegicus

Gene ID: 286993 | Gene type: protein coding

About Taok1

Summary

Enables several functions, including Myosin V binding activity; protein C-terminus binding activity; and protein serine/threonine kinase activator activity. Involved in protein autophosphorylation; regulation of actin Cytoskeleton organization; and regulation of microtubule Cytoskeleton organization. Predicted to be located in microtubule Cytoskeleton and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Orthologous to human TAOK1 (TAO kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Taok1 Products(1)

mRNA	Protein	Name
NM_173327.2	NP_775449.2	serine/threonine-protein kinase TAO1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables myosin V binding	IPI IPI: Inferred from physical interaction	24478457	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	18216281	RGD
enables protein kinase activator activity	IMP IMP: Inferred from mutant phenotype	9786855	RGD
enables protein kinase activity	IDA IDA: Inferred from direct assay	18216281	RGD
enables protein kinase binding	IDA IDA: Inferred from direct assay	9786855	RGD
enables protein kinase binding	IPI IPI: Inferred from physical interaction	18216281	RGD
enables protein serine/threonine kinase activator activity	IDA IDA: Inferred from direct assay	14517247	RGD
enables protein serine/threonine kinase activity	IDA IDA: Inferred from direct assay	14517247	RGD
enables protein serine/threonine kinase activity	IMP IMP: Inferred from mutant phenotype	9786855	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in protein autophosphorylation	IDA IDA: Inferred from direct assay	18216281	RGD
involved in protein phosphorylation	IMP IMP: Inferred from mutant phenotype	9786855	RGD
involved in regulation of actin cytoskeleton organization	IMP IMP: Inferred from mutant phenotype	18216281	RGD
involved in regulation of cytoskeleton organization	IDA IDA: Inferred from direct assay	14517247	RGD
involved in regulation of microtubule cytoskeleton organization	IMP IMP: Inferred from mutant phenotype	18216281	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

serine/threonine-protein kinase TAO1

thousand and one amino acid protein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-112136	TAO Kinase inhibitor 1		99.81%	Unkown
HY-RS14198	TAOK1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS18551	Taok1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS25033	Taok1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Taok1	NCBI	NCBI:57551

Name
Email *

	Sorry, but the email address you supplied was invalid.