2. Gene
  3. Ppif - peptidylprolyl isomerase F Gene

Ppif - peptidylprolyl isomerase F Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as CypD; CyP-D; PPIase

Gene ID: 282819 | Gene type: protein coding

About Ppif

Summary

Enables cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in regulation of apoptotic process and regulation of mitochondrial membrane permeability. Located in mitochondrial inner membrane and mitochondrial matrix. Orthologous to human PPIF (peptidylprolyl isomerase F). [provided by Alliance of Genome Resources, Apr 2022]

Ppif Products(1)

mRNA Protein Name
NM_172243.2 NP_758443.1 peptidyl-prolyl cis-trans isomerase F, mitochondrial precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables cyclosporin A binding IDA
IDA: Inferred from direct assay
1599421 RGD
enables peptide binding IDA
IDA: Inferred from direct assay
15233627 RGD
enables peptidyl-prolyl cis-trans isomerase activity IDA
IDA: Inferred from direct assay
1599421 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9820802 RGD
Biological Process GO Annotation Evidence Reference Source
involved in regulation of apoptotic process IDA
IDA: Inferred from direct assay
15233627 RGD
involved in regulation of mitochondrial membrane permeability IDA
IDA: Inferred from direct assay
15233627 RGD
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
9820802 RGD
is active in mitochondrial matrix IDA
IDA: Inferred from direct assay
20884751 RGD
located in mitochondrial matrix IDA
IDA: Inferred from direct assay
1599421 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peptidyl-prolyl cis-trans isomerase F, mitochondrial

PPIase F

cyclophilin D

cyclophilin F

rotamase F

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10951 PPIF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18784 Ppif Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25273 Ppif Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppif NCBI NCBI:10105