1. Gene
  2. Adamts16 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16 Gene

Adamts16 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16 Gene

Mus musculus
Gene ID: 271127 | Gene type: protein coding

About Adamts16

Summary

This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. This gene is co-expressed with the Wilms tumor protein, Wt1, in the developing glomeruli of embryonic kidneys. The encoded preproprotein undergoes proteolytic processing to generate an active enzyme. [provided by RefSeq, Jul 2016]

Adamts16 Products(1)

mRNA Protein Name
NM_172053.3 NP_742050.2 A disintegrin and metalloproteinase with thrombospondin motifs 16 preproprotein
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within branching involved in ureteric bud morphogenesis IMP
IMP: Inferred from mutant phenotype
23661704 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

A disintegrin and metalloproteinase with thrombospondin motifs 16

a disintegrin-like and metallopetidase (reprolysin type) with thrombospondin type 1 motif, 16

a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 16 preproprotein

Orthologs Information

Species Symbol Source ID
Homo sapiens Adamts16 NCBI NCBI:170690